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个人简历
教育经历
1987 - 1990 , 毕业 , 硕士 , 西北农林科技大学
1982 - 1986 , 毕业 , 学士 , 西北农林科技大学
1982 - 1986 , 毕业 , 学士 , 西北农林科技大学
科研领域描述
研究兴趣:
1． 主要从事水稻矮缩病毒及水稻黑条矮缩病毒矮缩病毒基因及编码蛋白功能的研究。
2． 抗呼肠孤病毒化合物的筛选及其抗病毒机制的研究。
1． 主要从事水稻矮缩病毒及水稻黑条矮缩病毒矮缩病毒基因及编码蛋白功能的研究。
2． 抗呼肠孤病毒化合物的筛选及其抗病毒机制的研究。
代表性论文
1. Ji X., Qian D., Wei C.H., Ye G.Y., Zhang Z.K., Wu Z.J., Xie L.H., Li Y. , Movement Protein Pns6 of Rice dwarf phytoreovirus Has Both ATPase and RNA Binding Activities, , PLoS ONE , 2011 , 6(9): e24986
2. Ji X, Wei CH, Li Yi. , Expression of rice dwarf phytoreovirus Pns6 and the specificity analysis of its monoclonal antibodies. , Science IN CHINA, Life Sciences , 2009 , 52:958-964
3. Gao F., Wang C.Z., Wei C.H., Li Y. , A branched-chain aminotransferase may regulate hormone levels by affecting KNOX genes in plants , Planta , 2009 , 230(4):611-23
4. Liu, H.J., Wei C.H., Zhong Y.W., Li Y. , Rice black-streaked dwarf virus outer capsid protein P10 has self-interactions and forms oligomeric complexes in solution. , Virus Research , 2007 , 127:34-42.
5. Liu, H.J., Wei C.H., Zhong Y.W., Li Y. , Rice black-streaked dwarf virus minor core protein P8 is a nuclear dimeric protein and represses transcription in tobacco protoplasts , FEBS Letter , 2007 , 581:2534-2540
6. Mao P., Duan M.R., Wei C.H., Li Y , WRKY62 Transcription factor acts downstream of cytosolic NPR1 and negatively regulates Jasmonate-responsive gene expression. , Plant & Cell Physiology , 2007 , 48(6):833-42
7. 6、 Li Y., Bao Y., Wei C. H.,Kang Z.S., Chen Z.L., Nelson R.S., Schiemann J., and Wu G. , Identification of the first gene with cell-to-cell movement function from A plant double-stranded RNA virus , Journal of Virology , 2004 , 78：5382-5389
2. Ji X, Wei CH, Li Yi. , Expression of rice dwarf phytoreovirus Pns6 and the specificity analysis of its monoclonal antibodies. , Science IN CHINA, Life Sciences , 2009 , 52:958-964
3. Gao F., Wang C.Z., Wei C.H., Li Y. , A branched-chain aminotransferase may regulate hormone levels by affecting KNOX genes in plants , Planta , 2009 , 230(4):611-23
4. Liu, H.J., Wei C.H., Zhong Y.W., Li Y. , Rice black-streaked dwarf virus outer capsid protein P10 has self-interactions and forms oligomeric complexes in solution. , Virus Research , 2007 , 127:34-42.
5. Liu, H.J., Wei C.H., Zhong Y.W., Li Y. , Rice black-streaked dwarf virus minor core protein P8 is a nuclear dimeric protein and represses transcription in tobacco protoplasts , FEBS Letter , 2007 , 581:2534-2540
6. Mao P., Duan M.R., Wei C.H., Li Y , WRKY62 Transcription factor acts downstream of cytosolic NPR1 and negatively regulates Jasmonate-responsive gene expression. , Plant & Cell Physiology , 2007 , 48(6):833-42
7. 6、 Li Y., Bao Y., Wei C. H.,Kang Z.S., Chen Z.L., Nelson R.S., Schiemann J., and Wu G. , Identification of the first gene with cell-to-cell movement function from A plant double-stranded RNA virus , Journal of Virology , 2004 , 78：5382-5389
执教课程
分子生物学实验 , 主讲课程 , 北京大学生命科学科学院 , 1998-2008
实验室简介
以昆虫为传毒介体的病毒病害一直是造成水稻产量损失最严重的病毒病害之一。水稻矮缩病毒 (Rice dwarf virus, RDV) 和水稻条纹叶枯病毒 (Rice stripe virus, RSV)是对我国水稻产生过严重产量损失的病毒病害。RDV由叶蝉以持久增殖型方式传播, RSV由灰飞虱以持久方式传播，且可经卵传播。迄今，对病毒如何引起病害研究很多，但是，病毒与介体传毒昆虫的相互作用研究的很少。本实验室主要研究方向：1）病毒与植物宿主的相互作用以及病毒侵染对宿主发育的影响和致病机制；2）植物宿主对病毒的防御机制与病毒的反防御机制；3）病毒与传播介体昆虫宿主的相互作用以及介体传播病毒机制；4）病毒对昆虫介体免疫系统的干扰和介体的抗病毒免疫机制。
