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冯仁青
邮  箱: rqfeng(AT)pku.edu.cn
职  称:
副教授
办公室地址: 北京市海淀区颐和园路5号,北京大学,金光生命科学大楼,100871
实验室地址: 北京市海淀区颐和园路5号,北京大学,金光生命科学大楼,100871
个人简历
教育经历
2000 - 2002 , 博士后,日本通商产业省生命工学工业技术研究所(Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Central 6, Higashi, Tsukuba, Ibaraki, Japan)
1996 - 1999 , 医学博士,日本筑波大学基础医学院,生物化学与分子肿瘤学(Department of Biochemistry and Molecular Oncology, Institute of Basic Medical Sciences ,University of Tsukuba, Tsukuba, Ibaraki , Japan)
1988 - 1991 , 医学硕士,河北医科大学基础医学院,生物化学
1981 - 1986 , 医学学士, 河北医科大学, 医学系
工作经历
2011 - 至今 , 博士生导师 , 北京大学生命科学学院
2002 - 至今 , 副教授 , 北京大学生命科学学院
荣誉奖励
首届“北京大学参政议政服务发展同心奖”先进个人, 2022
北京大学教学优秀奖 ,2018
北京大学优秀班主任 , 2017
北京大学东宝教师奖 , 2016
北京大学东宝教师奖 , 2011
北京大学优秀班主任 , 2008
科研领域描述
分子肿瘤学
代表性论文
1. Du LP, Li JY, Tian YL, Feng RQ*. Pleckstrin-2-promoted PPM1B degradation plays an important role in transforming growth factor-β-induced breast cancer cell invasion and metastasis. Cancer Science. 2023: 114 (6) , pp.2429-2444.(*Corresponding author).
2. Yang L, Li RC, Xiang B, Li YC, Wang LP, Guo YB, Liang JH, Wang XT, Hou T, Xing X, Zhou ZQ, Ye H, Feng RQ, Lakatta EG, Chai Z, Wang SQ* (2021) Transcriptional regulation of intermolecular Ca2+ signaling in ground squirrel cardiomyocytes: the myocardin- junctophilin axis. Proc. Natl. Acad. Sci. U.S.A. 2021;118:/e2025333118. Doi:10.1073/pnas.2025333118.
3.Cheng H, Wang S, Feng R*. STIM1 plays an important role in TGF-β-induced suppression of breast cancer cell proliferation. Oncotarget. 2016, 7(13): 16866-16878. DOI: 10.18632/oncotarget.7619 (*Corresponding author).
4.Yu Y, Yang R, Zhao X, Qin D, Liu Z, Liu F, Song X, Li L, Feng R*, Gao N*. Abrin P2 Suppresses Proliferation and Induces Apoptosis of Colon Cancer Cells via Mitochondrial Membrane Depolarization and Caspase Activation. Acta Biochimica et Biophysica Sinica, 2016, 48(5): 420-429.doi: 10.1093/abbs/gmw023(* Corresponding author).
5. Mahdi  SHA.,Cheng H., Li J.,Feng R*. The effect of TGF-beta-induced epithelial-mesenchymal transition on the expression of intracellular calcium-handling proteins in T47D and MCF-7 human breast cancer cells. Archives of Biochemistry and Biophysics, 2015, 583: 18-26. doi: 10.1016/j.abb.2015.07.008 (* Corresponding author).
6. Liu X; Du L; Feng R* , c-Src regulates cell cycle proteins expression through protein kinase B/glycogen synthase kinase 3 beta and extracellular signal-regulated kinases 1/2 pathways in MCF-7 cells , Acta Biochimica et Biophysica Sinica , 2013 , 45: 586-592. doi: 10.1093/abbs/gmt042.(* Corresponding author).
7. Liu X, Feng R* , Inhibition of epithelial to mesenchymal transition in metastatic breast carcinoma cells by c-Src suppression , Acta Biochimica et Biophysica Sinica , 2010 , 42(7): 496-501. DOI: 10.1093/abbs/gmq043. (* Corresponding author).
8. Liu X,Feng R*, Du L. , The role of enoyl-CoA hydratase short chain 1 and peroxiredoxin 3 in PP2-induced apoptosis in human breast cancer MCF-7 cells. , FEBS Letters. , 2010 , 584: 3185-3192. DOI: 10.1016/j.febslet.2010.06.002 (*Corresponding author).
9. Feng R*, Guo Z , Li J. , Efficient purification of GP-1D8 glycoprotein from human breast carcinoma tissue by immunoaffinity chromatography , Preparative Biochemistry and Biotechnology , 2008 , 38(4): 321-333 (* Corresponding author).
10. Feng R*, Liu X, Guo Z , Li J.  Purification and characterization of 66-kDa glycoprotein from human breast carcinoma , Cancer Sci , 2007 , 98: 1344-1349(* Corresponding author).
11. Feng R*, Du L, Guo Z , In vitro cultivation and differentiation of fetal liver stem cells from mice . Cell Res. , 2005 , 15(5):401-405(* Corresponding author).
12. Feng R, Kabayama A, Uchida K, Hoshino H, Miwa M.  Cell-free entry of human T-cell leukemia virus type 1 to mouse cells. , Jpn J Cancer Res , 2001 , 92(4):410-6.
13. Sun B, Feng R, Shoda M, Nitta T, Hanai S, Uchida K,Hoshino H, Miwa M. Cell-free HTLV-1 infection to mouse cells and expression , AIDS Research and Human Retrovirus , 2001 , 17(Suppl.1): S46-46
14. Feng R, Tanaka M, Abe H, Arashi N, Sun B, Uchida K, Miwa M. , Human T-cell leukemia virus type 1 can infect a wide variety of cells in mice , Jpn J Cancer Res , 1999 , 90(1):48-54
15. Fang J, Kushida S, Feng R, Tanaka M, Kawamura T, Abe H, Maeda N, Onobori M, Hori M, Uchida K, Miwa M.  Transmission of human T-cell leukemia virus type 1 to mice . J Virol , 1998 , 72(5):3952-7.
16. Fang J, Kushida S, Feng R, Tanaka M, Kikukawa H, Kawamura T, Uchida K, Miwa M. , Integration of HTLV-1 provirus into mouse transforming growth factor-alpha gene , Biochem Biophys Res Commun , 1997 , 233(3):792-5.
执教课程
抗体技术及应用 , 主持 , 北京大学 , 2005-至今 秋季学期
生化与分子生物学进展 , 讲课 , 北京大学 , 2004-至今 秋季学期
生物化学(下) , 讲课 , 北京大学 , 2002-2005
分子生物学实验 , 讲课 , 北京大学 , 2002-2004
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